The São Paulo Futebol Clube (Brazilian Portuguese: [sɐ̃w ˈpawlu futʃiˈbɔw ˈklubi] ), commonly referred to as São Paulo and sometimes anglicised as Saint Paul, is a professional football club in the Morumbi district of São Paulo, Brazil, founded in 1930. It plays in the Campeonato Paulista (São Paulo's premier state league) and the Campeonato Brasileiro Série A (the top tier of the Brazilian football league system). They are one of two clubs to have never been relegated from the top division, the other being Flamengo.

São Paulo is one of the most successful teams in Brazil with 22 state titles, 6 Campeonato Brasileiro titles, 1 Copa do Brasil title, 1 Supercopa do Brasil title, 3 Copa Libertadores titles, 1 Copa Sudamericana, 1 Supercopa Libertadores, 1 Copa CONMEBOL, 1 Copa Masters CONMEBOL, 2 Recopa Sudamericanas, 2 Intercontinental Cup and 1 FIFA Club World Cup. When São Paulo won the 2024 Supercopa do Brasil, it became the first Brazilian club to win all available trophies.

São Paulo was an inaugural member of the Clube dos 13, a group of Brazil's leading football clubs. The club's most consistent spell of success came in the 1990s under coach Telê Santana when it won two state titles, one national championship, two Copa Libertadores, two Recopa Sudamericanas, two Intercontinental Cups, one Supercopa Sudamericana, one Copa CONMEBOL and one Copa Masters CONMEBOL.

Its youth system produced many well-known players, including Kaká, the last Brazilian to win the Ballon d'Or.

São Paulo is the third best-supported club in Brazil, with over 22 million supporters. The team's traditional home kit is a white shirt with two horizontal stripes (one red and one black), white shorts, and white socks. Its home ground is the 72,039-seater MorumBIS, where it has played since 1960. The stadium was the venue for the Copa Libertadores finals of 1974, 1992, 1993, 1994, 2000, 2003, 2005 and 2006.

All five FIFA World Cups won by Brazil contained at least one São Paulo player, an honour shared with cross-city rivals Palmeiras.